We would like to congratulate Daša Pavc on successful PhD dissertation defense titled:
Influence of terminal ends and nature of cations on G-quadruplex formation.
We have seen you working hard day and night and now all the hardship has paid off. We are very proud of you.
7. 06. 2022
Engineering of materials with various bio-nanoapplications can rely on robust self-assembly of DNA e.g., short, guanine-rich oligonucleotides can self-assemble to long nanostructures, G-wires. Their structural details and self-assembly mechanism are crucial for optimization of G-wire’s properties, however they are poorly understood. Using NMR, we obtained a detailed insight into G-wire formation. We utilized this knowledge for modifications of parent oligonucleotide and thus preparation of G-wires of different properties. For visualization and further characterization we employed complementary methods.