A new paper in Nucleic Acids Research presents a high-resolution G-quadruplex structure of one of the major G-quadruplex species adopted by oligonucleotide which contains four d(G4C2) repeats, which have been linked to neurodegenerative disorders.
For more information read the original paper: here
4. 12. 2018
A study of specific loop interactions involving an adenine residue that can critically influence the folding pathway and structure of a G‐quadruplex has been highlighted as an Inside Cover in Angewandte Chemie journal.